| St. Mary's 48, Manual 29 | Dec. 6 | Details |
| St. Mary's 38, Holy Family 35 | Dec. 8 | Details |
| St. Mary's 65, Manitou Springs High School 39 | Dec. 14 | Details |
| St. Mary's 57, La Junta 31 () | Jan. 4 | Details |
| St. Mary's 72, Dolores Huerta Preparatory 3 () | Jan. 5 | Details |
| St. Mary's 58, Ellicott 26 | Jan. 11 | Details |
| St. Mary's 52, James Irwin Charter High School 16 () | Jan. 12 | Details |
| St. Mary's 57, Pueblo Centennial 25 | Jan. 16 | Details |
| St. Mary's 33, Trinidad 28 () | Jan. 17 | Details |
| Lamar 32, St. Mary's 30 () | Jan. 25 | Details |
| St. Mary's 42, La Junta 34 () | Jan. 26 | Details |
| St. Mary's 76, Dolores Huerta Preparatory 14 () | Feb. 1 | Details |
| St. Mary's 48, Ellicott 33 | Feb. 2 | Details |
| St. Mary's 38, James Irwin Charter High School 17 () | Feb. 7 | Details |
| Trinidad 42, St. Mary's 33 () | Feb. 9 | Details |
| St. Mary's 60, Pueblo Centennial 30 | Feb. 15 | Details |
| Lamar 44, St. Mary's 33 () | Feb. 16 | Details |
| Machebeuf 55, St. Mary's 47 | Feb. 19 | Details |
| St. Mary's 54, Florence 30 | Feb. 23 | Details |
| St. Mary's 41, The Classical Academy 31 | Feb. 26 | Details |
| St. Mary's 36, Lamar 25 | Mar. 1 | Details |
| St. Mary's 62, Estes Park High School 26 | Mar. 8 | Details |
| St. Mary's 39, Valley 26 | Mar. 9 | Details |
| St. Mary's 37, Kent Denver 34 | Mar. 14 | Details |
| Holy Family 53, St. Mary's 48 | Mar. 16 | Details |
